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ZKI-PH 1: AI-Fundamentals

Organisational unit , 16/06/2025

Research conducted within ZKI-PH 1 “AI-Fundamentals” focuses on the strategic development of novel AI technologies for public health applications. This will include designing fundamental AI methods, such as models for generating synthetic data, and novel analytical approaches to address methodological challenges. It will also include researching the ethical dimensions of AI applications in health and ensuring the quality and reliability of AI models used in medicine, society and public health.

Centre for Artificial Intelligence in Public Health Research

Organisational unit , 16/06/2025

The "Centre for Artificial Intelligence in Public Health Research" (ZKI-PH) is responsible for the strategic support of advances in the field of public health research using the latest AI-based technologies at the RKI. At ZKI-PH, the topics of bioinformatics, computational epidemiology, modern data visualisation as well as big data and systems analysis are combined with the central methodological building blocks of machine learning, AI, decision making research as well as the development of realistic computer simulations in the field of public health research. To meet these challenges, the ZKI-PH develops models and simulations for the corresponding subject areas, promotes the utilisation/transfer of existing solutions into public health applications and prepares the results and underlying …

Temporal trends in mortality due to coronary heart disease in Germany from 1998 to 2023

Publication , 11/06/2025

Abstract:Background: Coronary heart disease (CHD) is the leading cause of death in Germany. Comprehensive analyses of long-term trends in CHD mortality that also distinguish between acute myocardial infarction (AMI) and non-AMI-related chronic CHD are currently lacking.Method: Age-specific and age-standardised CHD mortality rates for the period 1998 – 2023 were calculated based on data from the cause-of-death statistics of the Federal Statistical Office of Germany. Annual percentage changes (APC) and average annual percentage changes (AAPC) were estimated using joinpoint regression analysis.Results: Between 1998 and 2023, the average annual change in age-standardised CHD mortality rates for women was -3.9 % ((-4.1) – (-3.7)) per year, compared with -3.2 % ((-3.3) – (-3.0)) for men. …

Application Form

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Publication , 05/06/2025

Request SCIENTIFIC USE FILERobert Koch InstituteResearch Data Centre

Centre for International Health Protection (ZIG)

Organisational unit , 29/05/2025

In a globalised world, where outbreaks of infectious diseases easily cross borders, national and international health protection are closely linked. At the same time, interactions between people, animals and the environment get ever more intense and create additional health risks. Therefore, resilient public health systems – from local to global – as well as expert exchange and international networking are crucial for public health. The “Centre for International Health Protection” at the Robert Koch Institute, abbreviated as “ZIG” in German, works with partner countries and international public health actors to strengthen public health systems and to respond to public health emergencies worldwide.

Programme for the Symposium “AI in Public Health Research”

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Publication

Programme for the Symposium “AI in Public Health Research” on 14th-15th May 2025

Data protection

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Publication , 26/05/2025

Symposium "Artificial Intelligence in Public Health Research"

Project group 5: Systems medicine of infectious diseases

Organisational unit , 23/05/2025

"Systems medicine of infectious diseases" aims to better understand infection and transmission mechanisms, as well as evolutionary dynamics, and to describe them using methods from the field of data science and mathematical modeling. This serves both to create basic knowledge and to better evaluate prevention-, treatment- and surveillance strategies. Our work ranges from the mathematical formulation of the problem, the development or adaptation of algorithms, the evaluation on biomedical data to the implementation and publication of open source software.

Risk of cardiovascular disease in Germany: results from GEDA 2022

Publication , 21/05/2025

Abstract:Background: Knowledge of the risk of cardiovascular disease (CVD) is important for its prevention.Methods: Data from a non-clinical test for the absolute risk of having a heart attack or stroke for the first time in the next ten years is available from 3,271 35- to 69-year-old participants in the GEDA 2022 study without a diagnosis of heart attack or stroke. This risk was categorised as low (< 5 %), still low (≥ 5 % – < 7.5 %), increased (≥ 7.5 % – < 10 %) and high (≥ 10 %). In addition, the self-perceived CVD risk was asked as almost no, low, moderate and high risk.Results: According to the CVD test, 73.5 % of adults were at low risk, 7.8 % were still at low risk, 6.0 % were at increased risk and 12.8 % were at high risk. In contrast, 28.7 % perceived themselves to be at …

Topic: Methods and Applications of Artificial Intelligence in Systematic Reviews

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Publication , 20/05/2025

Robert Koch Colloquium 2025 "Empowering Public Health: From Data to Global Health" 19,-20.05.2025