Projects and networks

Date:  04/03/2025

The Center for Biological Threats and Special Pathogens at the Robert Koch Institute (RKI) conducts research on questions of biological safety and in the context of highly pathogenic agents. This section shows a selection of national and international research projects and networks.

  • ABCM: Strengthening Madagascar's public health system (Duration: 2023-2025)

    The ABCM (‘Assessing and Building Capacities Madagascar Public Health System’) project supports Madagascar's health system in assessing and strengthening its own public health sector. In particular, a national reference laboratory is to be set up to expand the country's own diagnostic capacities. …

  • BIOCHEM-PSA: Disinfection of protective materials (Duration: 2025-2027)

    In the BIOCHEM-PSA project, disinfectants will be tested for their ability to inactivate both bacterial pathogens and chemical hazardous substances. These experiments will be carried out on different protective suit materials and evidence collection bags, and will take into account factors such as …

  • COUNTERACT: Medical Counter Measures against CBRN (Duration: 2022-2026)

    The "European agile network for medical COUNTERmeasures Against CBRN Threats" (COUNTERACT) project is about developing medical countermeasures (MCMs) against major CBRN threats and deploying them when necessary. To this end, COUNTERACT brings together numerous European partners to form a robust and …

  • EURL-PH-HEZB: EU Reference Laboratory for Public Health (Duration: 2025-2031)

    The EU Reference Laboratory for Public Health in the area of ‘High-risk, emerging and zoonotic bacterial pathogens’ (EURL-PH-HEZB) deals with known and emerging zoonotic bacterial pathogens. The EURL-PH-HEZB is one of six newly established EU reference laboratories for public health (EURLs). The aim …

  • German Biosecurity Programme (Duration: 2013-2025)

    The German Federal Foreign Office's Biosecurity Programme aims to prevent the misuse of pathogens and toxins, reduce the availability and spread of dangerous pathogens, and strengthen the national health capacities of partnered countries. The program consists of several individual projects that are …

  • GETRIB: Reducing water germs in drinking water pipes (Duration: 2023-2026)

    The GETRIB project analyses the interaction of biofilms in drinking water pipes with human pathogenic germs that have been introduced. In addition, the project will investigate which disinfection methods can reliably kill these pathogens and to what extent this is impeded by existing biofilms.

  • DryLab (UNSGM project) (Duration: 2021-2024)

    In order to support the Secretary-General's Mechanism (UNSGM), the bioinformatics skills of laboratories are to be trained and expanded. To this end, bioinformatic data sets will be provided as part of a "dry lab" EQAE, which will be analyzed and characterized by the participating laboratories with …

  • EFFO-CoE: Center of Excellence for HCID in Rwanda (Duration: 2021-2024)

    The EFFO - CoE ("Center of Excellence") project strengthens the clinical management of High Consequence Infectious Diseases (HCID) in Rwanda. To this end, Rwanda's first special isolation station (SIS) is being set up and a suitable training program for Rwandan healthcare staff is being established. …

  • EVAg: European Virus Archive (Duration: 2020-2024)

    As part of the "European Virus Archive Global" (EVAg) project, the EVA was developed into an international non-profit organization. With the participation of the RKI, the laboratories involved in the project organize the production, distribution, characterization and preservation of biological …

  • IDEAnet: Network for the identification of emerging pathogens in Sri Lanka (Duration: 2023-2025, follows "IDEA" 2017-2022)

    The IDEAnet project strengthens the diagnostic capacities for human pathogenic viruses in Sri Lanka. Measures are being developed to prevent outbreaks of highly pathogenic viruses and other pathogens in Sri Lanka. This includes in particular the establishment of a laboratory network to promote …

  • ImpliBoNT: Implementation of an animal test replacement method for botulism diagnostics (Duration: 2023-2026)

    The project "Implementation of a routine animal test replacement method for botulism diagnostics" (ImpliBoNT) aims to create acceptance for an innovative animal replacement method for botulinum neurotoxin diagnostics developed in preliminary projects. The project focuses on practical training …

  • InvOrigSmallPoxVac (Duration: 2020-2024)

    The project aims to sequence and analyze historical Variola vaccines (~1890 - 1976). The origin and evolution of the vaccinia virus, which was used for the worldwide eradication campaign, is still unknown.

  • ISO-BT: Bioterror diagnostics (Duration: 2023-2025)

    In the ISO-BT project, an isothermal amplification sequencing method is being implemented and evaluated using bioterror diagnostics as a model.

  • MEBBI 1-3: Management of contaminated attack sites (Duration: since 2017)

    In several successive research projects, German health and security authorities are developing a concept for the management of biologically contaminated attack sites under the coordination of the RKI. As it is not only a question of identifying the perpetrators but also of protecting the health of …

  • PLANT: Coping with bioterrorist threats from ricin and abrin (Duration: 2021-2024)

    The Franco-German joint project PLANT (Priority to threats posed by plant toxins: management, detection, forensics and therapeutics in a bioterrorism incident taken to the next level) aims to develop tools for the optimal management of the challenges associated with an attack involving the plant …

  • RefBIO (UNSGM project) (Duration: 2017-2024)

    The RefBIO project supports the laboratories nominated around the world by the UN member states for the Secretary-General's Mechanism (UNSGM) to prepare for diagnosis related to a biological attack. For example, RefBio offers laboratories the opportunity to train and develop their diagnostic skills …

  • SPOT: Detecting and combating zoonotic disease outbreaks in Tunisia (Duration: 2023-2025)

    Using a One Health concept, the SPOT project aims to strengthen Tunisia and its neighboring countries in their ability to quickly identify and combat potential future zoonotic outbreaks. To this end, innovative data on the occurrence and spread of zoonotic viruses in Tunisia and neighboring …

Completed projects

  • DEFERM: Optimising decontamination procedures (Duration: 2021-2024)

    The German-French DEFERM project is concerned with decontamination measures following an intentional or natural release of pathogenic microorganisms – including the emergency services that apply decontamination procedures.

  • EFFO: Efficiency through training to combat HCID in Africa (Duration: 2014-2020)

    The EFFO ("Efficiency through Training") project aims to combat diseases caused by High Consequence Infectious Diseases (HCID) by improving the capacity of healthcare systems through the provision of professional training for healthcare staff. EFFO has been implementing various sub-projects in …

  • EKOS: Safe initial treatment of HCID cases (Duration: 2016-2021)

    EKOS focused its research topic on the development of a new concept to ensure infectious patients with diseases caused by highly pathogenic pathogens in priority hospitals received safe medical care.

  • EU-Project: EQuATox (Duration: until 2014)

    In the EU project EQuATox ("Establishment of Quality Assurance for the Detection of Biological Toxins of Potential Bioterrorism Risk"), a European laboratory network was established that enables large EU-wide tests for the detection of biological toxins. Experts from security, health, and food …

  • ERIM: Emergency support for primary care clinicians (Duration: 2017-2021)

    The aim of the study was to devise supporting information material, which provided primary care clinicians with specific and evidence-based advice regarding unusual biological incidents. They will serve as templates for new material to be developed in the future as necessary.

  • EuroBioTox (Duration: 2018-2023)

    The EU project EuroBioTox (European programme for the establishment of validated procedures for the detection and identification of biological toxins) developed and validated improved analytical tools, reagents, and standard operating procedures based on realistic incident scenarios involving …

  • FUTURE International UZB (Duration: 2021-2023)

    Under the leadership of the RKI and Charité Universitätsmedizin Berlin, clinics in Uzbekistan were able to benefit from a telemedical intensive care network and the advantages of web-based learning during the COVID-19 pandemic as part of the "FUTURE International UZB" project. Through telemedicine, …

  • IDEA: Network for the identification of emerging pathogens in Sri Lanka (Duration: 2017-2022)

    The IDEA project supports the detection and investigation of public health-relevant viral outbreaks in Sri Lanka. Successor project is "IDEAnet" (2023-2025).

  • INFOKRI - Better information during the crisis (Duration: 2016-2018)

    "Prompt, target group-oriented, and targeted information in a crisis: Effective communication of information in extraordinary biological hazard situations" - this is what the INFOKRI project stands for. The project developed effective information services for extraordinary biological hazard …

  • KRILAWI: Prompt and targeted knowledge transfer for coping with biological hazards (Duration: 2021-2024)

    The aim of the KRILAWI project is to strengthen our healthcare system's ability to respond to crises in exceptional biological hazard situations through the timely and targeted transfer of knowledge. A resource-efficient knowledge management system is to be developed to ensure that all stakeholders …

  • Q-Co: Quarantine-Compliance (Duration: 2019-2021)

    The Q-Co project identified barriers and facilitating factors for quarantine compliance. On this basis, evidence-based practical recommendations were created for the public health service to implement epidemic hygiene measures effectively.

Networks

  • EKOS-Net: Network for HCID preparedness

    EKOS-Net is aimed primarily at hospitals and other medical facilities that want to prepare for the temporary care of patients with suspected infections from high consequence infectious diseases (HCID) outside of high level isolation units. The network is intended to provide hospitals with support in …

  • DTox-Net – German Toxin Laboratory Network

    The DTox-Net (Deutsches Toxin-Labornetzwerk; eng.: German Toxin Laboratory Network) is a nationwide network of institutions with expertise in the detection of biotoxins. The network was established in 2017 through association of around twenty laboratories from the public health service, …

  • EVD-LabNet: Expert laboratory network for (newly) emerging viral diseases

    EVD-LabNet creates and maintains a (pro)active and flexible network of European specialized laboratories active in patient diagnostics and supporting public health activities related to research activities on (emerging) viral diseases. The network continues the former "ENIVD" collaboration.

  • GHSAG LN

    The Global Health Security Initiative (GHSI) aims to better prepare health authorities for the dangers of international terrorism with biological, chemical, or radio-nuclear (CBRN) agents as well as natural outbreaks with pandemic potential. At a technical level, the "Laboratory Network Action …

  • GMI: Global Microbial Identifier

    The RKI participates in the Global Microbial Identifier (GMI) - a genomic epidemiological database for the global identification of microorganisms. The database stores WGS (Whole Genome Sequencing) data of microorganisms that can be used to identify relevant genes and compare genomes to detect …

  • GVN: Global Virus Network

    The RKI is a partner of the Global Virus Network (GVN). Leading scientific institutions and their scientists are organized in the GVN. The aim of this network is to improve medical virology worldwide and to strengthen the global response capacity for virologic threats and outbreaks.

  • NaLaDiBA: National Laboratory Network for BT Agents

    NaLaDiBA is a national laboratory network set up as part of a research project of the Federal Office for Civil Protection and Disaster Assistance (BBK). The network's activities focus on the detection of agents with bioterrorist potential from environmental samples.