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Diagnostics / Detection

Detection of relevant highly pathogenic agents

Beispiele hoch pathogener Agenzien: Quelle: RKI

The Robert Koch Institute detects disease-causing biological agents by means of different laboratory diagnostic methods. A selection of highly pathogenic agents and toxins as well as the detection methods used are listed by way of example.

Agent DiagnosticsRKI Contact
AbrinELISA, funct. methods, 
spectroscopy**
ZBS 3: Biological Toxins
Head of ZBS 3
Bacillus anthracisNucleic acid detection, EM*, cultivation, ELISA, spectroscopy**ZBS 2: Highly Pathogenic Microorganisms
Head of ZBS 2
Brucella melitensis, abortus, spp.Nucleic acid detection, EM*, cultivationZBS 2: Highly Pathogenic Microorganisms
Head of ZBS 2
Burkholderia mallei, pseudomalleiNucleic acid detection, EM*, cultivation, ELISA, spectroscopy**ZBS 2: Highly Pathogenic Microorganisms
Head of ZBS 2
Clostridium botulinum toxinsELISA, funct. method, spectroscopy**, cultivation, nucleic acid detection, typingZBS 3: Biological Toxins
Head of ZBS 3
Clostridium tetani toxincultivation, functional method, nucleic acid detectionZBS 3: Biological Toxins
Head of ZBS 3
Coxiella burnetiiNucleic acid detection, EM*, spectroscopy**ZBS 2: Highly Pathogenic Microorganisms
Head of ZBS 2
Francisella tularensisNucleic acid detection, EM*, cultivation, ELISA, spectroscopy**ZBS 2: Highly Pathogenic Microorganisms
Head of ZBS 2
RicinELISA, funct. method, spectroscopy**, nucleic acid detectionZBS 3: Biological Toxins
Head of ZBS 3
Staphylococcal enterotoxins, S. aureusCultivation, ELISA, spectroscopy**ZBS 3: Biological Toxins
Head of ZBS 3
Variola majorNucleic acid detection, EM*, ELISAZBS 1: Highly Pathogenic Viruses
Head of ZBS 1
Venezuelan equine encephalomyelitis virusNucleic acid detection, EM*, cultivation, ELISAZBS 1: Highly Pathogenic Viruses
Head of ZBS 1
Haemorrhagic fever virusesNucleic acid detection, EM*, cultivation, ELISAZBS 1: Highly Pathogenic Viruses
Head of ZBS 1
Yersinia pestisNucleic acid detection, EM*, cultivation, ELISA, spectroscopy**ZBS 2: Highly Pathogenic Microorganisms
Head of ZBS 2

*Electron microscopy (EM) carried out by ZBS 4

**Spectroscopy carried out by ZBS 6

Date: 01.12.2020