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WHO Reference Laboratories
Regional Reference Laboratory of the WHO/Europe for Poliomyelitis
Head: Sabine Diedrich
Deputy: Sindy Böttcher
Tasks
- Molecular-epidemiological analysis of selected picornavirus serotypes
- Intratypic differentiation of poliovirus isolates using molecular methods (PCR, sequencing in different genome regions)
- Support of European countries in the diagnostic clarification of selected AFP cases (cultivation, typing and sequencing)
Providing of reference material (cell culture)
Date: 01.03.2016
Regional Reference Laboratory of the WHO/Europe for Measles and Rubella
Head: Annette Mankertz
Deputy: Sabine Santibanez
Tasks
- Detection and genetic characterization of currently circulating measles and rubella viruses
- Submission of sequence data to MeaNS and RubeNS database (WHO)
- External quality assessment for European measles and rubella laboratories (serology, virus detection, genotyping, data submission)
- Development of test procedures and of SOPs, training of European colleagues
- Investigations on the efficacy of MMR vaccines (mapping of immunorelevant epitopes, analysis of vaccine failures)
- Evaluation of the population immunity against measles, mumps and rubella virus
Date: 01.03.2016