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Unit 36: Respiratory Infections

Head:
Walter Haas
Deputy:
Stefan Kröger

The unit is responsible for surveillance, monitoring, epidemiological research and development of preventive concepts for respiratory infections. The current focus is on influenza, tuberculosis and legionellosis.

Moreover, the unit advises the expert public and supports the Federal States in the clarification of outbreaks caused by respiratory pathogens.

Tasks

Influenza

  • Surveillance and all year up-to-date reporting about acute respiratory diseases on the population level (see also Working Group on Influenza and GrippeWeb)
  • Advice on influenza pandemic planning (in charge of the scientific part of the National Pandemic Plan)
  • Secretariat for the Expert Advisory Board on pandemic Acute Respiratory Infections
  • Recommendations on infection prophylaxis and management

Tuberculosis

  • Surveillance and regular reporting on the epidemiology of tuberculosis including drug resistance
  • Co-ordination of the national control strategy
  • Support of international contact tracing
  • Advice on mandatory reporting and questions related to contact tracing and risk of infection

Legionellosis

  • Surveillance and epidemiological reporting
  • Tracking of national and international disease clusters (ELDSNET)
  • Advice on the mandatory reporting and questions related to the investigation of infection sources

National and international co-operation

  • With universities, non-government organisations (NGOs) and public health institutes
  • With international disease-specific networks as a national contact point for the European Centre for Disease Prevention and Control (ECDC) and the World Health Organisation (WHO)

Projects

(selection)

  • Assessment of the disease burden caused by influenza in Germany
  • Development of an electronic surveillance system for the recording of acute respiratory diseases based on the diagnostic key according to ICD-10 in medical information systems for physicians (interface documentation for AIS providers)
  • Identification of risk diseases, underlying and concurrent illnesses and complications for influenza and community-acquired pneumonia in Germany based on computer-aided surveillance using ICD-10 diagnosis codes
  • Epidemiological analysis of the additional data on influenza A(H1N1)pdm collected during the pandemic
  • Estimate of the influenza excess mortality
  • Monitoring of the efficacy of influenza vaccination against seasonal influenza (vaccination effectiveness)
  • Epidemiology of tuberculosis in special population groups (including senior citizens, children, people with a migration background, population in big cities)
  • Linkage of molecular typing and tuberculosis notification data
  • Analysis of drug resistance patterns for tuberculosis
  • Investigation of the influence of epidemiological factors on the tuberculosis treatment outcome
  • Epidemiology of the HIV/tuberculosis comorbidity in Germany
  • Occurrence, diagnosis and therapeutic success of non-tuberculosis mycobacterial diseases in children

Date: 23.04.2021

Publications

  • Balabanova Y, Fiebig L et al. (2017): Multidrug-resistant TB in Eastern region of the EU: is the shorter regimen an exception or a rule?
    Thorax 72 (9): 850-852. Epub Feb 16. doi: 10.1136/thoraxjnl-2016-209841. more

  • Brodhun B (2017): Häufung von reiseassoziierten Legionellen-Erkrankungen in Dubai.
    Epid Bull (3): 30. doi: 10.17886/EpiBull-2017-003. more

  • Fiebig L, Kohl TA, Popovici O, Mühlenfeld M, Indra A, Homorodean D, Chiotan D, Richter E, Rüsch-Gerdes S, Schmidgruber B, Beckert P, Hauer B, Niemann S, Allerberger F, Haas W (2017): A joint cross-border investigation of a cluster of multidrug-resistant tuberculosis in Austria, Romania and Germany in 2014 using classic, genotyping and whole genome sequencing methods: lessons learnt
    Euro Surveill. 22 (2): pii: 30439. Epub Jan 12. doi: 10.2807/1560-7917.ES.2017.22.2.30439. more

  • Herfst S, Böhringer M, Karo B et al. (2017): Drivers of airborne human-to-human pathogen transmission
    Curr. Opin. Virol. 22: 22–29. Epub 2016 Dec 2. doi: 10.1016/j.coviro.2016.11.006. more

  • Reuß A, Preuß U, Buda S, Prahm K, Buchholz U, an der Heiden M, Biere B, Wedde M, Schweiger B (2017): Vorläufige Ergebnisse zur Wirksamkeit der saisonalen Influenza-Impfung bei ambulant behandelten Patienten in der Saison 2016/2017 in Deutschland.
    Epid Bull (6): 61-62. doi: 10.17886/EpiBull-2017-007. more

  • Buchholz U, Buda S et al. (2017): Monitoring schwerer Lungenerkrankungen durch Influenza-Infektionen in den Saisons 2012/2013 bis 2014/2015.
    Epid Bull (8): 75–81. doi: 10.17886/EpiBull-2017-008. more