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ZBS 3: Biological Toxins

Brigitte Dorner
Martin Dorner

Tasks include:

  • Diagnostics of microbial toxins that could be used for bioterrorist attacks using techniques based on cell biological, genetical and serological parameters, as well as chromatographic methods and mass spectroscopy
  • Development of SOPs for diagnostics
  • Provision of reference samples, reference bacterial strains and standards, storage of diagnostic material
  • Adaptation of the diagnostic materials to the expected sample material
  • Development of strategies for the detection of novel and modified toxins and agents
  • Research on the pathogenesis of the diseases induced
  • Interlaboratory experiments to assure the quality of diagnostics
  • Contribution to the development of standard therapies
  • Characterisation of adherence/colonisation factors in toxin-producing and tissue-damaging bacteria

Date: 15.02.2014